Non-uniformly Sampled Double-TROSY hNcaNH Experiments for NMR Sequential Assignments of Large Proteins
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چکیده
منابع مشابه
Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins.
The initial step of protein NMR resonance assignments typically identifies the sequence positions of 1H-15N HSQC cross-peaks. This is usually achieved by tediously comparing strips of multiple triple-resonance experiments. More conveniently, this could be obtained directly with hNcaNH and hNcocaNH-type experiments. However, in large proteins and at very high fields, rapid transverse relaxation ...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2006
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja0584222